Biophotonics in veterinary medicine: the first steps toward clinical translation
Date
2019-02-20
Authors
Cugmas, Blaž
Spīgulis, Jānis
Journal Title
Journal ISSN
Volume Title
Publisher
SPIE
Abstract
In this paper, we analyzed the current situation and the potential of biophotonics and biomedical optics in veterinary
medicine. Promising optical techniques such as optical coherence tomography, pulse oximeter, and hyperspectral
imaging have been clinically translated into human medicine. But even though human and small animal medicine share
personalized and state-of-the-art approach, biophotonics remains rarely exploited in the canine and feline medicine.
However, there are some biophotonics studies in veterinary oncology which addressed tumor diagnosis (skin and
subcutaneous tumors), prognosis (lymphoma), and therapy (clear surgical margins). Visible and near-infrared
spectroscopy served for measuring various physiological parameters related to circulation, and photobiomodulation
therapy was often used for the management of wounds, skin conditions, and orthopedic problems. In the research, the
most popular clinically translated technique is thermography which was applied for the diagnosis of orthopedic problems
and diseases as infections and hyperthyroidism. The future optical devices for small animals such as dogs and cats
should be robust and resilient to damage (e.g., due to biting, chewing), offering user-friendly and short measurements. In
veterinary oncology, biophotonics could replace invasive fine-needle aspiration procedure. The potential of a pulse
oximeter for pet monitoring has yet to be explored. What is more, photobiomodulation efficiency should be tested in an
extensive clinical (in vivo) study. The technique would be very beneficial in dentistry which currently requires expensive
and risky anesthesia.
Description
Keywords
biophotonics , biomedical optics , veterinary medicine , clinical translational , small animals , pulse oximeter , optical coherence tomography , dogs , Research Subject Categories::NATURAL SCIENCES::Physics::Atomic and molecular physics
Citation
Blaž Cugmas, Jānis Spīgulis, "Biophotonics in veterinary medicine: the first steps toward clinical translation ," Proc. SPIE 10885, Optical Diagnostics and Sensing XIX: Toward Point-of- Care Diagnostics, 108850I (20 February 2019); doi: 10.1117/12.2507980