Tetrazīna ciklu saturoši proteīnu linkeri biokonjugācijā
Date
2022
Authors
Strazdiņa, Renāte
Journal Title
Journal ISSN
Volume Title
Publisher
Latvijas Universitāte
Abstract
Tetrazīna ciklu saturoši proteīnu linkeri biokonjugācijā. Strazdiņa R., zinātniskais vadītājs doc. Kļimenkovs I., bakalaura darbs, 39 lappuses, 49 attēli, 33 literatūras avoti, 3 pielikumi. Latviešu valodā. PROTEĪNU LINKERI, 1,2,3-TRIAZOLS, TETRAZĪNS, ALDEHĪDGRUPA Izstrādāta 7 soļu sintēze proteīnu linkerim, kas satur 1,2,3-triazola ciklu, kā arī tetrazīna ciklu un aldehīdgrupu piesaistīšanai mērķa molekulām.
Tetrazine contaning protein linkers in bioconjugation. Strazdiņa R., supervisor doc. Kļimenkovs I. Bachelor’s thesis, 39 pages, 49 figures, 33 literature references, 3 appendices. In Latvian. PROTEIN LINKERS, 1,2,3-TRIAZOLE, TETRAZINE, ALDEHYDE GROUP A 7-step synthetic sequence has been devised to obtain a protein linker containing a 1,2,3-triazole cycle, as well as a tetrazine cycle and an aldehyde group to ensure linking to target molecules.
Tetrazine contaning protein linkers in bioconjugation. Strazdiņa R., supervisor doc. Kļimenkovs I. Bachelor’s thesis, 39 pages, 49 figures, 33 literature references, 3 appendices. In Latvian. PROTEIN LINKERS, 1,2,3-TRIAZOLE, TETRAZINE, ALDEHYDE GROUP A 7-step synthetic sequence has been devised to obtain a protein linker containing a 1,2,3-triazole cycle, as well as a tetrazine cycle and an aldehyde group to ensure linking to target molecules.
Description
Keywords
Ķīmija , PROTEĪNU LINKERI , 1,2,3-TRIAZOLS , TETRAZĪNS , ALDEHĪDGRUPA