Diazonamīda A neciklisko analogu sintēze
Date
2019
Authors
Vasiļevska, Anna
Journal Title
Journal ISSN
Volume Title
Publisher
Latvijas Universitāte
Abstract
Diazonamīda A neciklisko analogu sintēze. Vasiļevska A., zinātniskie vadītāji: prof., Dr. chem. Sūna E., Mg. chem. Kazak M. Maģistra darbs, 78 lappuses, 70 attēli, 6 tabulas, 81 literatūras avots. Latviešu valodā. Darbā veikta diazonamīda A neciklosko analogu sintēze, izmantojot litiētā 2,4’-bioksazola reakciju ar ketoniem un Negishi šķērssametināšanu. Ir izstrādātās divas metodes 2,4’-bioksazolu sintēzei. Literatūras apskatā aplūkota informācija par 2,4’-bioksazolu sintēzes metodēm un 2,4’-bioksazola modificēšanas iespējām C5’ pozīcijā.
Synthesis of Diazonamide A Acyclic Analogues. Vasiļevska A., supervisors: prof., Dr. chem.. Sūna E., Mg. chem. Kazak M. Master thesis, 78 pages, 70 figures, 6 tables, 81 literature reference. In Latvian. The work is dedicated to the synthesis of diazonamide A acyclic analogues, using the reaction of lithiated 2,4’-bisoxazole with ketones and Negishi cross-coupling. Two synthesis methods of 2,4’-bisoxazole are developed. The literature review illustrates the synthetic approach towards 2,4’-bisoxazoles and modification possibilities of C5’ position of 2,4’-bisoxazole.
Synthesis of Diazonamide A Acyclic Analogues. Vasiļevska A., supervisors: prof., Dr. chem.. Sūna E., Mg. chem. Kazak M. Master thesis, 78 pages, 70 figures, 6 tables, 81 literature reference. In Latvian. The work is dedicated to the synthesis of diazonamide A acyclic analogues, using the reaction of lithiated 2,4’-bisoxazole with ketones and Negishi cross-coupling. Two synthesis methods of 2,4’-bisoxazole are developed. The literature review illustrates the synthetic approach towards 2,4’-bisoxazoles and modification possibilities of C5’ position of 2,4’-bisoxazole.
Description
Keywords
Ķīmija , Diazonamīds , 2,4'-Bioksazols , Negishi šķērssametināšana , Litijēšana