Skimager for the objective erythema estimation in atopic dogs
Date
2020-02-19
Authors
Cugmas, Blaž
Olivry, Thierry
Olivrī, Alla
Spīgulis, Jānis
Journal Title
Journal ISSN
Volume Title
Publisher
International Society for Optics and Photonics (SPIE)
Abstract
In this study, the severity of canine skin erythema was assessed objectively for the first time. Atopic dermatitis (AD) is a common canine inflammatory and pruritic skin disease associated with an allergic reaction to exogenous allergens. The monitoring of skin erythema over time with lesion severity scales like the CADESI-4 is an essential diagnostic and research tool, especially for clinical trials. Currently, the erythema assessment is subjective due to visual estimation. In our study, we calculated the erythema index (EI) in 14 atopic dogs based on the analysis of multispectral skin images taken with the Skimager device. The relationship between the EI and a visual erythema estimation was modeled by linear regression with the first-order polynomial. The coefficient of determination (r squared) reached 0.81. Based on such high correlation, we conclude that optical measurements could replace the visual estimation of erythema in atopic dogs and, thus, improve the validity of skin lesion severity scales in dogs.
Description
Keywords
Atopic dermatitis , Erythema severity , Erythema Index , Multispectral imaging , Skimager , Dogs , Disease severity scales , CADESI-4
Citation
Blaž Cugmas, Thierry Olivry, Alla Olivrī, and Jānis Spīgulis "Skimager for the objective erythema estimation in atopic dogs", Proc. SPIE 11211, Photonics in Dermatology and Plastic Surgery 2020, 1121110 (19 February 2020); https://doi.org/10.1117/12.2544664