Skimager for the objective erythema estimation in atopic dogs

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dc.contributor.authorCugmas, Blaž
dc.contributor.authorOlivry, Thierry
dc.contributor.authorOlivrī, Alla
dc.contributor.authorSpīgulis, Jānis
dc.date.accessioned2020-03-02T06:24:32Z
dc.date.available2020-03-02T06:24:32Z
dc.date.issued2020-02-19
dc.description.abstractIn this study, the severity of canine skin erythema was assessed objectively for the first time. Atopic dermatitis (AD) is a common canine inflammatory and pruritic skin disease associated with an allergic reaction to exogenous allergens. The monitoring of skin erythema over time with lesion severity scales like the CADESI-4 is an essential diagnostic and research tool, especially for clinical trials. Currently, the erythema assessment is subjective due to visual estimation. In our study, we calculated the erythema index (EI) in 14 atopic dogs based on the analysis of multispectral skin images taken with the Skimager device. The relationship between the EI and a visual erythema estimation was modeled by linear regression with the first-order polynomial. The coefficient of determination (r squared) reached 0.81. Based on such high correlation, we conclude that optical measurements could replace the visual estimation of erythema in atopic dogs and, thus, improve the validity of skin lesion severity scales in dogs.en_US
dc.identifier.citationBlaž Cugmas, Thierry Olivry, Alla Olivrī, and Jānis Spīgulis "Skimager for the objective erythema estimation in atopic dogs", Proc. SPIE 11211, Photonics in Dermatology and Plastic Surgery 2020, 1121110 (19 February 2020); https://doi.org/10.1117/12.2544664en_US
dc.identifier.doi10.1117/12.2544664
dc.identifier.urihttps://dspace.lu.lv/dspace/handle/7/50049
dc.language.isoengen_US
dc.publisherInternational Society for Optics and Photonics (SPIE)en_US
dc.relationinfo:eu-repo/grantAgreement/EC/H2020/745396/ EU/ Multimodal Spectral Imaging for Canine Skin Erythema Estimation: from the Lab to the Clinic/DogSPECen_US
dc.relation.ispartofseriesProc. SPIE 11211;1121110
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtopic dermatitisen_US
dc.subjectErythema severityen_US
dc.subjectErythema Indexen_US
dc.subjectMultispectral imagingen_US
dc.subjectSkimageren_US
dc.subjectDogsen_US
dc.subjectDisease severity scalesen_US
dc.subjectCADESI-4en_US
dc.titleSkimager for the objective erythema estimation in atopic dogsen_US
dc.typeinfo:eu-repo/semantics/articleen_US
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